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About The Computational Neuropsychiatry Lab
The Computational Neuropsychiatry Lab aims to bridge the gap between clinical practice and research, neurology, psychiatry, physics and psychology in order to re-formulate our understanding of the human self and its pathologies. We work with and for neurological and psychiatric patients in the department of neurology, neuropsychiatry clinic, invasive neurophysiological unit and in the operation room. We use state of the art computational methods applied directly on clinical data, particularly tailored to improve clinical management and scientific understanding of neuropsychiatric disorders. Our multidisciplinary team of medical doctors, physicists, computer scientists and psychologists perform electrophysiological and metabolic recordings in healthy subjects and neuropsychiatric patients. We perform sophisticated analyses and modeling in order to better understand the human "self" in health and disease.

Our lab facilities include fMRI, multi-channel EEG, intracranial EEG, virtual reality, and direct cortical stimulation. We are located within the Department of Neurology and have a close collaboration with the Departments of Psychiatry, Neuroradiology and Neurosurgery, enabling us to investigate and help patients in real-time. We develop approaches to address the specific medical needs of neuropsychiatric patients and clinicians. Our main interests involve cortex-related functional conditions including epilepsy, neurodegenerative diseases, conversive and dissociative disorders, amnesias, disorientation states and different cognitive disturbances and misperceptions. By combining direct clinical involvement and cutting-edge computational methods we are able to challenge the customary context of the human “self” and to reframe neuropsychiatry, and at the same time to develop effective patient-tailored clinical tools.

transient connectivity disturbances in transient global amnesia EEG measurement of psychoactive drug effects common brain system for orientation in space, time and person
Discontinuity of cortical gradients reflects sensory impairment out-of-body experience transient connectivity disturbances in transient global amnesia

Selected publications:

Peer et al., Reversible functional connectivity disturbances during transient global amnesia. Annals of Neurology 2014. link

Peer et al., Brain system for mental orientation in space, time and person. PNAS 2015. link

Saadon-Grosman et al., Discontinuity of cortical gradients reflects sensory impairment. PNAS 2015. link

Arzy S, Idel M. Kabbalah: A Neurocognitive Approach to Mystical Experiences. Yale University Press 2015. link

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